Endocrine Abstracts

Transthyretin (TTR) is well documented as a carrier for thyroid hormones. It also binds retinol binding protein preventing its filtration trough the kidneys and therefore is involved in delivering retinol to target cells. Moreover, TTR sequesters amyloid-beta impairing its deposition in nervous tissues and possibly contributing to its removal. Despite its importance in mammalian physiology, there are few studies regarding the regulation of TTR synthesis. In silico analy...